Zhang Zhang Selected Research

Imatinib Mesylate (Gleevec)

2/2016	Structure-Activity Relationship Study of Rakicidins: Overcoming Chronic Myeloid Leukemia Resistance to Imatinib with 4-Methylester-Rakicidin A.
2/2013	Identification of GZD824 as an orally bioavailable inhibitor that targets phosphorylated and nonphosphorylated breakpoint cluster region-Abelson (Bcr-Abl) kinase and overcomes clinically acquired mutation-induced resistance against imatinib.

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Zhang Zhang Research Topics

Disease

80	Neoplasms (Cancer) 01/2024 - 01/2008
18	Breast Neoplasms (Breast Cancer) 10/2023 - 06/2011
16	Neoplasm Metastasis (Metastasis) 10/2023 - 09/2015
11	Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung) 03/2024 - 11/2013
10	Lung Neoplasms (Lung Cancer) 01/2023 - 01/2014
6	Hepatocellular Carcinoma (Hepatoma) 10/2023 - 12/2009
6	Carcinoma (Carcinomatosis) 01/2021 - 03/2006
5	Stomach Neoplasms (Stomach Cancer) 12/2023 - 07/2012
5	Hypoxia (Hypoxemia) 01/2023 - 11/2014
5	Carcinogenesis 01/2023 - 02/2015
5	Squamous Cell Carcinoma (Epidermoid Carcinoma) 04/2022 - 06/2015
4	Leukemia 12/2022 - 04/2011
4	Colonic Neoplasms (Colon Cancer) 01/2022 - 05/2010
3	Pancreatic Neoplasms (Pancreatic Cancer) 01/2024 - 01/2019
3	Cardiovascular Diseases (Cardiovascular Disease) 03/2023 - 01/2010
3	Melanoma (Melanoma, Malignant) 01/2023 - 01/2008
3	Neurodegenerative Diseases (Neurodegenerative Disease) 08/2022 - 08/2018
3	Ductal Carcinoma 07/2022 - 01/2009
3	Wounds and Injuries (Trauma) 06/2022 - 01/2015
3	Inflammation (Inflammations) 01/2022 - 01/2015
3	Pain (Aches) 01/2022 - 03/2016
3	Prostatic Neoplasms (Prostate Cancer) 11/2016 - 01/2012
3	Hyperemia 01/2015 - 06/2011
2	Cardiac Arrhythmias (Arrythmia) 01/2024 - 01/2022
2	Anemia 10/2023 - 09/2010
2	Lymphoma (Lymphomas) 01/2023 - 11/2016
2	Hematologic Neoplasms (Hematological Malignancy) 11/2022 - 04/2020
2	Colorectal Neoplasms (Colorectal Cancer) 10/2022 - 01/2022
2	Pneumonia (Pneumonitis) 01/2022 - 02/2020
2	Periodontitis 01/2022 - 01/2020
2	Heart Failure 01/2022 - 01/2021
2	Brain Ischemia (Cerebral Ischemia) 12/2021 - 01/2021
2	Triple Negative Breast Neoplasms 11/2021 - 07/2014
2	Osteosarcoma (Osteogenic Sarcoma) 07/2021 - 04/2018
2	BCR-ABL Positive Chronic Myelogenous Leukemia (Chronic Myelogenous Leukemia) 05/2021 - 02/2016
2	Cognitive Dysfunction 03/2021 - 01/2019
2	Myocardial Infarction 01/2021 - 11/2014
2	Glioma (Gliomas) 01/2020 - 01/2015
2	Epilepsy (Aura) 01/2020 - 01/2019
2	Neuroblastoma 10/2019 - 01/2019
2	Parkinson Disease (Parkinson's Disease) 09/2019 - 08/2018
2	Cicatrix (Scar) 04/2019 - 01/2010
2	Alzheimer Disease (Alzheimer's Disease) 01/2019 - 01/2017
2	Pathologic Constriction (Stenosis) 07/2017 - 01/2015

Drug/Important Bio-Agent (IBA)

19	Proteins (Proteins, Gene)FDA Link 01/2023 - 01/2012
14	Phosphotransferases (Kinase)IBA 10/2023 - 04/2011
12	Biomarkers (Surrogate Marker)IBA 01/2024 - 07/2014
6	Therapeutic UsesIBA 01/2022 - 11/2014
6	MicroRNAs (MicroRNA)IBA 01/2021 - 06/2014
6	Oxygen (Dioxygen)IBA 01/2019 - 01/2010
5	ErbB Receptors (EGF Receptor)IBA 03/2024 - 01/2018
4	Epidermal Growth Factor (EGF)IBA 01/2024 - 04/2018
4	CateninsIBA 06/2022 - 08/2017
4	Progesterone Receptors (Progesterone Receptor)IBA 10/2019 - 06/2011
4	Estrogen ReceptorsIBA 10/2019 - 01/2010
4	AntigensIBA 08/2018 - 09/2010
4	Cisplatin (Platino)FDA LinkGeneric 01/2018 - 07/2012
4	Adenosine (Adenocard)FDA LinkGeneric 07/2017 - 06/2011
3	Tyrosine Kinase InhibitorsIBA 03/2024 - 01/2018
3	1-phenyl-3,3-dimethyltriazene (PDT)IBA 01/2023 - 01/2016
3	Peptides (Polypeptides)IBA 06/2022 - 01/2022
3	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 01/2022 - 03/2006
3	Hormones (Hormone)IBA 01/2020 - 09/2016
3	ParaffinIBA 09/2017 - 01/2009
3	LigandsIBA 01/2015 - 05/2010
2	Small Interfering RNA (siRNA)IBA 12/2023 - 07/2012
2	Anti-Bacterial Agents (Antibiotics)IBA 10/2023 - 02/2016
2	radix ophiopogonis drug combination radix ginseng fructus schizandrae (Shen Mai)IBA 03/2023 - 01/2023
2	Photosensitizing Agents (Photosensitizers)IBA 01/2023 - 01/2016
2	pyrotinibIBA 01/2023 - 01/2022
2	CytokinesIBA 01/2023 - 01/2015
2	STAT3 Transcription Factor (Signal Transducer and Activator of Transcription 3)IBA 01/2023 - 12/2010
2	Janus Kinase 3IBA 11/2022 - 01/2022
2	6-methyladenineIBA 10/2022 - 01/2021
2	Peptide Hydrolases (Proteases)FDA Link 08/2022 - 01/2014
2	NucleotidesIBA 07/2022 - 06/2021
2	Circular RNAIBA 04/2022 - 01/2021
2	TropomyosinIBA 01/2022 - 01/2019
2	Capsules (Microcapsules)IBA 01/2022 - 01/2022
2	CalciumIBA 01/2022 - 01/2021
2	Neuroprotective AgentsIBA 12/2021 - 05/2017
2	RNA (Ribonucleic Acid)IBA 01/2021 - 01/2020
2	Messenger RNA (mRNA)IBA 01/2021 - 07/2012
2	human ERBB2 proteinIBA 01/2020 - 06/2017
2	Brain-Derived Neurotrophic Factor (BDNF)IBA 10/2019 - 01/2019
2	Indicators and Reagents (Reagents)IBA 08/2019 - 01/2014
2	Gefitinib (Iressa)FDA Link 01/2018 - 11/2013
2	GZD856IBA 12/2017 - 05/2016
2	Folic Acid (Vitamin M)FDA LinkGeneric 10/2017 - 07/2014
2	8- dibenzothiophen- 4- yl- 2- morpholin- 4- yl- chromen- 4- oneIBA 10/2017 - 02/2015
2	Formaldehyde (Formol)FDA Link 09/2017 - 02/2016

Therapy/Procedure

27	Therapeutics 01/2024 - 05/2010
13	Drug Therapy (Chemotherapy) 01/2023 - 07/2012
8	Radiotherapy 10/2017 - 07/2012
5	Chinese Traditional Medicine (Traditional Chinese Medicine) 01/2021 - 01/2010
4	Immunotherapy 12/2023 - 06/2022
3	Photochemotherapy (Photodynamic Therapy) 01/2023 - 01/2016
3	Oral Administration 11/2022 - 12/2018
2	Transplantation 01/2022 - 11/2014
2	Transcranial Direct Current Stimulation 01/2020 - 01/2019